MyBioSource.com's ITGA1 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot.
Description
ITGA1 chain associates with the beta 1 (ITGB1) chain to form a heterodimer that unctions as a dual laminin/collagen receptor in neural cells and hematopoietic cells. ITGA1 has a 06-amino acid I domain in its N-terminal half, followed by 3 divalent cation-binding sites and a -terminal transmembrane domain with a short cytoplasmic tail. It also has 28 potential N-glycosylation ites. Human ITGA1 was expressed in a mouse fibroblast cell line as a 180-kD protein. ITGA1 is involved in the early remodeling of osteoarthritic cartilage and plays an essential role in the regulation of esenchymal stem cell proliferation and cartilage production. It also plays an essential role in the egulation of MSC proliferation and cartilage production